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Quantifying Paroxysmal Atrial Fibrillation

Determining the full amount of atrial fibrillation (AF) a patient is enduring may be the key to personalized AF management. How could using this measure in addition to standard stroke risk profiles enhance clinical decision making for patients with paroxysmal atrial fibrillation (PAF)?

See an Expert's Take on AF Burden and the KP-RHYTHM Study2

Dr. Michael Mirro, Chief Academic and Research Officer of Parkview Health shares his perspective on managing PAF patients and how the results from the KP-RHYTHM study could impact clinical practice. View the full conversation below.
 

Introduction

Dr. Mirro talks about the impact that AF has on public health.

 

The Challenges of Managing Paroxysmal AF

Dr. Mirro discusses some of the decisions clinicians need to make when managing PAF patients and how they can be challenging.
 

Thoughts on the AHA Scientific Statement1

Dr. Mirro gives his take on the AHA Scientific Statement discussing the concept of AF burden.

 

The KP-RHYTHM Study: Design and Results

Dr. Mirro discusses the KP-RHYTHM study results and provides his thoughts on how they could influence more personalized decision-making around stroke prevention strategies in PAF patients.
 

Is Short-term Monitoring Enough to Assess AF Burden?

Dr. Mirro explains why 24-to-48-hour monitoring is inadequate to accurately measure true AF burden.

 

Discussing Anticoagulation with Your Patient

Dr. Mirro addresses the challenge of managing patients who are reluctant to start anticoagulation therapy and how using AF burden can further substantiate the need to begin treatment.
 

The Challenge of Medication Adherence

Dr. Mirro talks about how AF burden can help clinicans reinforce medication adherence in patients by precisely clarifying their stroke risk.

 

Using AF Burden for On-going Patient Management

Dr. Mirro suggests that reassessing AF burden at regular intervals can help inform critical decisions about therapy modification for patients with paroxysmal atrial fibrillation.

Learn More About KP-RHYTHM

Click below for an overview of the KP-RHYTHM study design and results including insights from the AHA Scientific Statement.

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References

1. Atrial Fibrillation Burden: Moving Beyond Atrial Fibrillation as a Binary Entity: A Scientific Statement From the American Heart Association Lin Y. Chen, Mina K. Chung, Larry A. Allen, Michael Ezekowitz, Karen L. Furie, Pamela McCabe, Peter A. Noseworthy, Marco V. Perez, Mintu P. Turakhia and On behalf of the American Heart Association Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; Council on Quality of Care and Outcomes Research; and Stroke Council Circulation. 2018;CIR.0000000000000568, originally published April 16, 2018 https://doi.org/10.1161/CIR.0000000000000568

2. Go AS, Reynolds K, Yang J, et al. Association of Burden of Atrial Fibrillation With Risk of Ischemic Stroke in Adults With Paroxysmal Atrial FibrillationThe KP-RHYTHM Study. JAMA Cardiol. Published online May 16, 2018. doi:10.1001/jamacardio.2018.1176

This study was supported by a research grant by: